


Prospectus supplement, you should rely on the information set forth in this prospectus supplement. If the information contained in this prospectus supplement differs or varies from the information contained in the accompanying prospectus or any document incorporated by reference herein that was filed with the SEC before the date of this Generally, when we refer to this prospectus, we are referring to both parts of this document combined. The second part, the accompanying prospectus, provides more general information. Prospectus and the documents incorporated by reference therein.

The first part is the prospectus supplement, which describes the specific terms of this offering and also adds to and updates information contained in the accompanying This document is in two parts and is part of the registration statement on Form F-3 that we filed with the SecuritiesĪnd Exchange Commission, or SEC, using a shelf registration process. The date of this prospectus supplement is January 7, 2021ĬAUTIONARY STATEMENT REGARDING FORWARD-LOOKING STATEMENTSĭESCRIPTION OF SHARE CAPITAL AND ARTICLES OF ASSOCIATIONĮNFORCEABILITY OF CERTAIN CIVIL LIABILITIESĬHANGE IN REGISTRANTS CERTIFYING ACCOUNTANT Any representation to the contrary is a criminal offense. Securities and Exchange Commission nor any state securities commission nor the FSMA has approved or disapproved of these securities orĭetermined if this prospectus supplement or the accompanying prospectus is truthful or complete. See the information contained under Risk Factors sectionīeginning on page S-7 of this prospectus supplement and the documents incorporated by reference herein. Investing in ADSs involves a high degree of risk. ∼YAD. On January 5, 2021, the last reported sale price of the ADSs as reported on the Nasdaq Global Market was $8.21 per ADS.

See Plan of Distribution.ĪDSs representing our ordinary shares are listed on the Nasdaq Global Market under the symbol We will pay the expenses incurred in connection with the issuance of the securities under the Will be based upon formulas set forth in the Purchase Agreement depending on the type of purchase notice we submit to Lincoln Park from time to time. underwriter within the meaning of Section 2(a)(11) of the Securities Act, as amended, or the Securities Act. This prospectus supplement and the accompanying prospectus also cover the resale of these ADSs by Lincoln Park to the public. Share, no nominal value, that we may issue to Lincoln Park Capital Fund, LLC (Lincoln Park) from time to time under a Purchase Agreement that we entered into with Lincoln Park on January 6, 2021 (the Purchase Agreement). This prospectus supplement relates to the issuance and sale of up to $40,000,000 of our American Depositary Shares, or ADSs, each representing one ordinary All rights reserved.In the Form of American Depositary Shares MLPF&S makes available investment products managed or distributed by BofA™ Global Capital Management, an affiliate of Bank of America Corporation. Investment products,Īre Not Insured by Any Federal Government AgencyĪre Not a Condition to Any Banking Service or Activity Investing in securities involves risks, and there is always the potential of losing money when you invest in securities. and affiliated banks, Members FDIC and wholly owned subsidiaries of Bank of America Corporation. Banking products are provided by Bank of America, N.A. Trust and fiduciary services are provided by Merrill Lynch Trust Company, a division of Bank of America, N.A. Insurance and annuity products are offered through Merrill Lynch Life Agency Inc., a licensed insurance agency and wholly owned subsidiary of Bank of America Corporation. Merrill Lynch Wealth Management makes available products and services offered by Merrill Lynch, Pierce, Fenner & Smith Incorporated (MLPF&S), a registered broker-dealer and Member Securities Investor Protection Corporation (SIPC), and other subsidiaries of Bank of America Corporation.
